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Genes 211Ʊ
October 27, 2020

Top Headlines
 

Scientists Discover How a Common Mutation Leads to 'Night Owl' Sleep Disorder

People with delayed sleep phase disorder are unable to fall asleep until late at night (often after 2 a.m.) and have difficulty getting up in the ...

Researchers Solve 'Protein Paradox' and Suggest Way to Exploit Cancer Weakness

Researchers have discovered how thus far a mysterious function of the so-called MCM proteins protect the human cells against DNA instability, which ...

Transcription Factors May Inadvertently Lock in DNA Mistakes

A team of researchers has found that transcription factors have a tendency to bind strongly to 'mismatched' sections of DNA, i.e. sections of the genome that were not copied correctly. The strong ...

Congress Must Clarify Limits of Gene-Editing Technologies

How the next Congress decides to handle the issue editing human sperm and eggs will affect the science, ethics and financing of genomic editing for decades to come, said a law professor who studies ...
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Proton Regulator of Essential Cancer microRNA

New findings unveil that a 'hidden' layer of regulation by which the intrinsic dynamic ensemble of miRNA processing intermediates can direct the outcome of important biological processes in ...

Neuron-Based Gene Expression Study Reveals Insights on Fear and Its Regulation

The expression of a gene called CREB in certain neurons may function as a switch to regulate feelings of fear and its ...

Researchers Reveal Why Heat Stress Damages Sperm

Biologists have used the model organism Caenorhabditis elegans to identify molecular mechanisms that produce DNA damage in sperm and contribute to male infertility following exposure to ...

Coronavirus Mutations Show Early Safety Measures and Restrictions Limited Viral Spread

Scientists analyzed genomic information from over 6,000 samples of SARS-CoV-2, the coronavirus behind the COVID-19 pandemic. Results show that early measures in states such as California and ...

A Promising Discovery Could Lead to Better Treatment for Hepatitis C

Virologists have identified a critical role played by a cellular protein in the progression of Hepatitis C virus infection, paving the way for more effective treatment. No vaccine currently exists ...

Antiretroviral Therapy Can't Completely Stop Accelerated Cell Aging Seen in HIV

Untreated HIV infection is linked with epigenetic changes that suggest rapid aging. A new study shows that antiretroviral therapy given over two years was unable to completely restore age-appropriate ...

Multiple Sclerosis as the Flip Side of Immune Fitness

211Ʊ half of the people with multiple sclerosis have the HLA-DR15 gene variant. A study has now shown how this genetic predisposition contributes to the development of the autoimmune disease ...

Tracking the SARS-CoV-2 Virus With Genome Sequencing

A new study shows how next generation genetic sequencing can track mutations in the SARS-CoV-2 virus, which can in effect help with transmission tracing, diagnostic testing accuracy and vaccine ...

Highly Effective Tumor Detection Strategy for Common Childhood Brain Tumors

A team of scientists have developed a way to more accurately both detect and monitor a common type of pediatric brain cancer, setting the stage for giving clinicians a real-time view into how the ...

Observed COVID-19 Variability May Have Underlying Molecular Sources

People have different susceptibilities to SARS-CoV-2, the virus behind the COVID-19 pandemic, and develop varying degrees of fever, fatigue, and breathing problems -- common symptoms of the illness. ...

DNA: At Our Cores, We're All Strengthened by 'Dumbbells'

Scientists detail the structure of dumbbell-like sequences in DNA during interphase that suggest several unseen aspects of chromosome configuration and ...

Genome Archeologists Discover Path to Activate Immune Response Against Cancer

Ancient embedded elements in our DNA from generations past can activate a powerful immune response to kill cancer cells like an ...

Tumor DNA in Spinal Fluid Could Help Doctors Better Monitor Childhood Brain Cancer

Researchers have demonstrated that a new liquid biopsy approach overcomes traditional barriers to quickly and efficiently diagnose and monitor high-grade pediatric ...

Delivering Proteins to Testes Could Someday Treat Male Infertility

According to the Mayo Clinic, about 15% of couples are infertile, and male infertility plays a role in over one-third of these cases. Often, problems with sperm development are to blame. Now, ...

Hidden States of the COVID-19 Spike Protein

Computer modeling of the COVID-19 virus on supercomputers showed that the spike protein visits an intermediate state before it can dock to the receptor protein on the host cell membrane. This ...

Scientists Take Major Step Toward Angelman Syndrome Gene Therapy

Babies born with a faulty maternal copy of the UBE3A gene will develop Angelman syndrome, a severe neurodevelopmental disorder with no cure and limited treatments. Now, for the first time, scientists ...

Targeting the Shell of the Ebola Virus

As the world grapples with COVID-19, the Ebola virus is again raging. Researchers are using supercomputers to simulate the inner workings of Ebola (as well as COVID-19), looking at how molecules ...

The Biological 'Record' of Extremely Preterm Birth Differs in Men and Women

Researchers have found distinct effects of adversity early in life in the genomes of men compared to women who were born extremely ...

A Promising New Tool in the Fight Against Melanoma

A new study has revealed that a key blood marker of cancer could be used to select the most effective treatment for ...

CRISPR Meets Pac-Man: New DNA Cut-and-Paste Tool Enables Bigger Gene Edits

Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more quickly with a new tool for cutting larger ...

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